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| SKU Code | LBFN-010FC |
| Host | Mouse |
| Reactivity | Human |
| Tested Application | FC |
| Size | 20T | 100T |
| Price | POR |
| FITC Anti-Human CD329 Antibody(K8) - Specifications | |
| Synonyms | Siglec-9| Sialic acid-binding Ig-like lectin-9 antibody |
| Isotype | IgG1, κ |
| Form | Liquid |
| Conjugation | FITC |
| Conjugation Information | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm |
| Clonality | Monoclonal |
| Clone ID | K8 |
| UniProt ID | Q9Y336 |
| Storage | PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| Host | Mouse |
|---|---|
| Reactivity | Human |
| Tested Application | FC |
Siglecs are cell surface receptors belonging to the immunoglobulin superfamily that recognize sugar antigens. The extracellular domain of siglec-9 contains an IgV region, which binds sialic acid, followed by two IgC regions. Siglec 9 and siglec 6-8,10-12 are CD33 (siglec 3) like siglecs, which have two ITIMs in the cytoplasmic tails, suggesting their functional involvement in signal transduction. It is highly expressed on neutrophils and monocytes, and at lower levels on the subpopulations of T and B lymphocytes and NK cells. Siglec-9 plays a role in negative regulation of T cell activation, and it also affects neutrophil apoptosis.
Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Staining of normal human peripheral blood cells with FITC Anti-Human CD329(Siglec-9) Antibody(
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