FASN Antibody

SKU Code LBFN-001PH
Host Rabbit
Reactivity Human, Mouse
Tested Application ELISA, IF, IHC, WB
Size 100μg
Price POR
SKU: LBFN-001PH

Description

FASN Antibody - Specification
Alternative Names Fatty acid synthase|Type I fatty acid synthase|FASN|FAS antibody
Clonality Polyclonal
Form Liquid
Purity ≥95%
Isotype IgG
Immunogen fatty acid synthase
UniProt ID P49327
Observed MW 280 kDa
Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
UniProt ID P49327

Additional information

Host

Rabbit

Reactivity

Human, Mouse

Background

The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

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