anti- Transferrin antibody

Catalogue No. 92980AB
Size 100µg / liquid Form
Synonyms Beta 1 metal binding globulin, DKFZp781D0156, PRO1557, PRO2086, Serotransferrin, Siderophilin, TF, Transferrin
Host: Rabbit
Reactivity: Human, Mouse, Rat
Isotype: IgG
Tested Application: ELISA, WB, IHC, IF
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Description

Product Name anti- Transferrin antibody
Catalogue No. 92980AB
Size 100µg
Form liquid
Purification Immunogen affinity purified
Purity ≥95% as determined by SDS-PAGE
Host Rabbit
Clonality Polyclonal
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Serotransferrin (TF) is a 77 kDa secreted protein which is also named as transferrin, siderophilin, beta-1 metal-binding globulin and belongs to a family of homologous iron-binding glycoproteins that encompasses lactoferrin (found both intracellular and in secretions, including milk) , melanotrasferrin (present on melanoma cells) and ovotransferrin (present in egg white) . TF is a multi-function protein with a primary role in transporting iron in a safe, redox-inactive state from absorption to utilization or storage sites around the body. The association of Tf with the immune system derives from its ability to restrict serum free-iron levels, creating low-iron environments where the infection capacity of pathogenic microorganisms is limited. TF is expressed predominantly in the liver and secreted in plasma, but lower amounts can be synthesized in other tissues such as the brain and the testis

IMMUNOGEN INFORMATION

Immunogen transferrin
Observed MW 77 kDa

APPLICATION

Tested Application ELISA, WB, IHC, IF
Recommended Dilution WB: 1:200-1:1000; IHC: 1:20-1:200

 

IMAGES

Immunohistochemistry of paraffin-embedded human hepatocirrhosis using 92980AB  (TF antibody) at dilution of 1:50  

mouse kidney tissue were subjected to SDS PAGE followed by western blot with 92980AB  (TF antibody) at dilution of 1:400  

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