Description
| Product Name | anti- COX2 antibody |
| Catalogue No. | 70401BSAB |
| Size | 100µg |
| Form | liquid |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
BACKGROUND
| COX2 (Prostaglandin G/H synthase 2; PTGS2) mediates the formation of prostaglandins from arachidonate. Its subunit structure is homodimer. The fully N-glycosylated PTGS2 is 72–74 kDa and the aglycosylated is 66 kDa(PMID:19656660 ). It also expresses a band of 39 kDa after unspecific cleavage(PMID:17509125 ). The 50 kDa band of fragmented PTGS2 has also previously been detected in AD brains(PMID:14724276 ). |
IMMUNOGEN INFORMATION
| Immunogen | prostaglandin-endoperoxide synthase 2(prostaglandin G/H synthase and cyclooxygenase) |
| Observed MW | 50 kDa, 80 kDa |
APPLICATION
| Tested Application | ELISA, WB, IHC, |
| Recommended Dilution | WB: 1:500 – 1:2000; IHC: 1:50 – 1:200 |
IMAGES
| Immunohistochemistry of paraffin-embedded human liver using 70401BSAB(cox2 antibody) at dilution of 1:100 |  |
| Various lysates were subjected to SDS PAGE followed by western blot with 70401BSAB(PTGS2 antibody) at dilution of 1:600 |  |
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