Link Biotech

DNA Oligo Synthesis

We provide high-quality, customized DNA and RNA oligonucleotide synthesis and a wide selection of oligo probes for molecular diagnostic applications. Supporting projects across diverse areas—from molecular diagnostics to advanced genome editing.

Contatc Us

What We Strive For

Link Biotech provide high-quality DNA oligo synthesis and modification services, including standard DNA primers, modified DNA oligos, qPCR primers and probes, NGS primers and probes.  We have quality control standards for different applications, such as scientific research and in vitro diagnostics.

We are committed to delivering the highest quality products to meet the needs of researchers worldwide. We offer a comprehensive range of custom oligonucleotide synthesis and purification services tailored to customer requirements. 

If you have any questions or for additional information on Oligo Synthesis Serv, kindly contact us at support@linkbiotech.co.in OR linkbiotech@gmail.com

Featured DNA Oligo Synthesis Services

Custom DNA Oligo Synthesis

Link Biotech utilizes advanced high-throughput oligo synthesizers to deliver a comprehensive range of DNA oligonucleotide synthesis services. Each oligo is produced under stringent quality control at every stage of synthesis, ensuring outstanding accuracy and consistency. Our HPLC-purified oligos offer superior quality at highly competitive prices, delivering exceptional value without compromising performance. Ideal for PCR amplification and a wide variety of molecular biology applications.

Services Advantages:
  • Stable Quality: Strict quality control standards, high purity, low molecular weight bias, batch-to-batch stability
  • Customized Services: Meet customer requirements of different specifications and purities
  • Technical Support: our experienced team provides professional support and prompt pre-sales and after-sales services.
  • Fast Turnaround Time: production in as soon as, on-time delivery rate is >95%
  •  

Link Biotech provides customized DNA oligo modification/labeling services, including more than 100 modifications such as biotin, digoxigenin, phosphate, thiol, sulfhydryl, amino, special bases, and a variety of fluorescent groups. 100% of the delivered modified probes/primers have passed mass spectrometry detection to ensure accuracy and purity, meeting the needs of scientific research and industrial-grade modified primers/probes.

Oligo Modification Position:

Oligo Modification

qPCR (quantitative polymerase chain reaction), also called real-time PCR, is a molecular biology technique used to quickly and sensitively measure the amount of a specific gene in a DNA or RNA sample. Primers and probes are one of the key factors affecting the success of qPCR and the reliability of its results.

Link Biotech has established an advanced oligo synthesis and modification technology platform with an experienced technical team to provide customized qPCR primers and probes. We are committed to assisting your research and diagnostic applications with high accuracy and reliability of qPCR primers and probes

Services Advantages:
  • GMP-like clean room, strict control of pollution sources, avoiding NTC interference
  • Advanced production technology ensures product accuracy, high purity, and stable fluorescent labeling

  • Standardized operation and strict quality control to ensure batch-to-batch stability of primers/probes

Next-generation sequencing (NGS) has been instrumental in various applications, including whole-genome sequencing, targeted resequencing, RNA-Seq, and ChIP-Seq, among others, and it has significantly accelerated biological and medical research. Link Biotech professional technical team utilizes our advanced oligo synthesis and modification technology platform to provide adapters for NGS library construction, blockers and capture probes for hybridization capture, and primers for multiplex PCR. We are committed to supporting your NGS experiments with high-quality primers and probes NGS Primers & Probes

The principle of FISH (Fluorescence in Situ Hybridization) probe is to use fluorescently labeled short nucleic acid fragments (DNA or RNA probes) to form a stable hybrid structure with specific nucleic acid sequences in the target sample through base pairing. During the experiment, the DNA or RNA in the sample is first denatured into a single strand, and then the probe binds to the target sequence. The fluorescent signal carried by the bound probe can be directly observed under a fluorescence microscope, thereby achieving precise positioning and quantitative analysis of the target gene or chromosome. This technology is widely used in gene expression research, chromosome abnormality detection and cancer diagnosis.

FISH Probes

Service Advantages:
  • Professional design: Accurately match the target sequence, improve specificity, and reduce background signal interference. Mixed FISH probe sets are available.
  • High-quality synthesis: The delivered FISH probes are purified by HPLC to ensure product quality.
  • Multiple fluorescent labels: Provide Cy3, Cy5, FAM and other conventional dyes. Different fluorescent dyes can be selected according to the customer’s multiple detection needs to distinguish the signals of multiple targets.
  • Compatibility: Applicable to various sample types such as cells and tissue sections.

Short Tandem Repeat (STR) is a DNA repeat sequence composed of 2-6 base units in the genome, also called microsatellite DNA or simple repeat sequence (SSR). Since the number of core unit repeats is variable and abundant among individuals, STR is highly polymorphic and widely exists in the coding and non-coding regions of eukaryotic genomes. As an important genetic marker system, STR It is widely used in many fields such as gene mapping, tumor analysis, forensic identification, paternity testing and genetic analysis.

Based on our advanced oligonucleotide synthesis and modification technology platform, Our professional team has optimized the dye and purification process, and developed STR primer quality standards that meet forensic identification applications, providing you with high-quality fluorescently labeled STR primers.

Link Biotech has successfully developed single-stranded circular DNA (CssDNA) synthesis technology, providing researchers in gene expression, gene therapy, and vaccine development with a powerful new tool. 

Why Choose CssDNA Synthesis Service? 

  • Enhanced Stability: The circular DNA structure prevents degradation in cells, ensuring long-term stable expression. 
  • High Transfection Efficiency: Compared to linear DNA, CssDNA offers superior transfection efficiency, making it particularly suitable for gene therapy and DNA vaccine development.
  • Versatile Applications: Whether for gene expression vectors, virology studies, nanotechnology, or gene editing, our CssDNA provides reliable and stable support. 
  • Custom Solutions: From sequence design to synthesis, we offer fully customized services to meet your specific research needs. 

Link Biotech production team has accumulated more than ten years of experience in oligo synthesis and modification, and cooperates with professional bioinformatics and AI technical teams to provide you with one-step PCR assay design and development services from design, synthesis to verification. After receiving your requirements, we will perform AI-assisted design of your assay, synthesize oligos in our ISO9001 certified laboratory and deliver the product according to your needs or conduct further validation.

We are committed to helping speed up your time to market with professional technologies and high-quality services.

Service Features:
  • Guaranteed Design Result: For professional design and validation package, if the first design does not achieve the desired results, we will provide an alternative assay design at no additional charge. 
  • Computer-Assisted: Utilize in-silico tools for simulation evaluation to minimize unnecessary trial and error during wet-lab assay optimization.
  • Professional Oligonucleotide Synthesis:  advanced oligo synthesis technology platform, with a variety of modifications and fluorescent labels to choose from