Link Biotech

CUSTOM ANTIBODY

Phospho-Akt (Ser473) Antibody

SKU Code LBFN-002PH
Host Rabbit
Reactivity Human, Mouse, Rat
Tested Application ELISA, IHC, WB
Size 100μg
Price POR
SKU: LBFN-002PH
Categories: , ,

Description

Phospho-Akt(Ser473) Antibody - Specification
Alternative Names RAC-alpha serine/threonine-protein kinase|Protein kinase B (PKB)|Protein kinase B alpha (PKB alpha)|Proto-oncogene c-Akt|RAC-PK-alpha|AKT1|PKB|RAC antibody
Clonality Monoclonal
Form Liquid
Purification Protein A+G purification
Purity ≥95%
Isotype IgG1
Immunogen v-akt murine thymoma viral oncogene homolog 1
UniProt ID P31749
Observed MW 60 kDa
Recommended dilution WB: 1:1000-1:4000; IHC: 1:50-1:200
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months

Additional information

Host

Mouse
Reactivity

Human, Mouse, Rat

Background

The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. This antibody detects all the members of AKT with phospho-modification.

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